Multiple Technology Appraisal (UK NICE)

A multiple technology appraisal (MTA) is an appraisal undertaken by NICE that compares one or more technologies used in one or more indications of interest. The evidence assessment is undertaken by an external assessment group (EAG). Formal consultees are invited to provide submissions; this includes technology sponsors as well as clinical experts, NHS commissioning experts and patient experts. The MTA process is approximately 14 weeks longer than the single technology assessment (STA) process. Given this longer timeline and the independence of marketing authorisation timings for new medicines in the same indication(s), MTAs are much less common than STAs for pharmaceutical therapies. Detailed guidance on the MTA process is available in the NICE health technology evaluation manual.